• 学前教育
  • 小学学习
  • 初中学习
  • 高中学习
  • 语文学习
  • 数学学习
  • 英语学习
  • 作文范文
  • 文科资料
  • 理科资料
  • 文档大全
  • 当前位置: 雅意学习网 > 高中学习 > 正文

    正交试验优选延胡索碱总生物碱的提取工艺:延胡索所含的生物碱

    时间:2019-04-07 03:10:20 来源:雅意学习网 本文已影响 雅意学习网手机站

      [摘要]目的 研究延胡索总生物碱的提取工艺。方法 采用正交设计法,以延胡索总生物碱和延胡索乙素为检测指标,采用紫外分光光度法和高效液相色谱法测定含量。结果 最佳提取工艺为:60%乙醇,提取3次,每次1.5 h,溶剂用量8倍。结论 优选的延胡索总生物碱提取工艺简便,适合工业化生产。
      关键词 : 正交试验 提取工艺 延胡索总生物碱 延胡索乙素
      Optimization of Extraction Process of total Alkaloids from Corydalis yanhusuo by Orthogonal Experiment
      Lu Ziming1,2,Liu Dan2,Liu Wenjuan2,Liang Junqing 2,Yao Bing2,Tu Pengfei1*
      (1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; 2 Beijing Yiling Pharmaceutical Co., Ltd., Beijing 100027, China)
      Abstract:Objective: To investigate the extraction process of total alkaloids from Corydalis yanhusuo. Methods: The extraction process of total alkaloids from Corydalis yanhusuo was optimized by L9(34) orthogonal experiment with the contents of total alkaloids and tetrahydropalmatine as the index which were determined by UV and HPLC. Results: to investigate the effects of extraction time, concentration alcohol, extraction times and solvent volume on the extraction of the total alkaloids of yanhusuo: The optimal extraction process was: adding 8 times of 60% alcohol, refluxing and extracting for 3 times, 1.5 h per time. Conclusion: The optimal extraction process of Corydalis yanhusuo is simple, and practical for industrial production.
      Key words:Orthogonal experiment; Extraction process; Corydalis yanhusuo; Total alkaloids; Tetrahydropalmatine
      中图分类号:R917 文献标识码:A 文章编号:1004-7484(2012)04-0103-03
      

    推荐访问:延胡索 生物碱 正交 优选

    • 文档大全
    • 故事大全
    • 优美句子
    • 范文
    • 美文
    • 散文
    • 小说文章